Ultrasensitive and highly selective fluorescence probe of nitrogen-doped graphene quantum dots and zinc oxide decorated carbon foam incorporated molecularly imprinted polymer for trace sparfloxacin determination

Chansud, N., Kaewnok, R., Nurerk, P., Davis, F. and Bunkoed, O. (2023) Ultrasensitive and highly selective fluorescence probe of nitrogen-doped graphene quantum dots and zinc oxide decorated carbon foam incorporated molecularly imprinted polymer for trace sparfloxacin determination. Materials Today Communications, 35. p. 105687. ISSN 23524928

[thumbnail of This is a post-peer-review, pre-copyedit version of an article published in Journal of Vocational Behavior. The final authenticated version is available online at: https://doi.org/10.1016/j.mtcomm.2023.105687] Text (This is a post-peer-review, pre-copyedit version of an article published in Journal of Vocational Behavior. The final authenticated version is available online at: https://doi.org/10.1016/j.mtcomm.2023.105687)
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Abstract

A fluorescent probe was fabricated for the determination of sparfloxacin. The nanocomposite probe was constructed by incorporating nitrogen-doped graphene quantum dots, zinc oxide decorated carbon foam and magnetite into a matrix formed from a molecularly imprinted polymer. The fabricated nanoprobe was characterized and the fabrication and determination conditions were optimized to obtain the highest sensitivity. The determination of sparfloxacin was based on the decreasing of emission response of the nanocomposite probe when the target analyte rebinds to the inherent recognition sites of the fluorescent probe. Under the best conditions, the quenching of fluorescence was linear in the range of 0.10–100.0 μg L−1 (R2 = 0.991) with the limit of detection being 0.10 μg L−1. The nanocomposite probe exhibited high specificity with an imprinting factor of 7.93. This optosensor was used to determine sparfloxacin in milk and good recoveries were observed ranging from 93.0 % to 100.8 % with RSDs lower than 5 %. The results also agreed with the results obtained using a chromatographic method but the developed method has higher sensitivity, at lower cost and faster determination procedure. In addition, the developed optosensor can be simply modified for highly selective determination of other trace levels of target compounds by changing the template with minor changes in determination conditions.

Item Type: Articles
Uncontrolled Keywords: Sparfloxacin, Nitrogen-doped graphene quantum dots, Fluorescence, Zinc oxide, Carbon foam, Selective polymer
Subjects: Q Science > QR Microbiology
R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
T Technology > T Technology (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: Academic Areas > Department of Engineering, Computing and Design
SWORD Depositor: Publications Router Jisc
Depositing User: Publications Router Jisc
Date Deposited: 19 Apr 2023 11:24
Last Modified: 19 Apr 2023 11:24
URI: https://eprints.chi.ac.uk/id/eprint/6738

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